Homosexuality runs through my mother's side of the family. She has 3 sisters and two of them plus herself went through a lesbian phase at one point. On top of that, a close cousin of mine is full blown gay (not flamboyant, just strictly gay) and no one anywhere has a problem with it.
My father's side, however, is filled with upper-class white-trash, if that makes sense. Basically, they have money and they're all idiots. My grandparents never mentioned gays, but always had a disgusted expression when ever they were watching TV and anything close to a homosexual came on.
My parents are very accepting to my sexuality (bi, by the way) ever since I came out after a discussion of a close friend coming out. They were first skeptical, thinking I was just playing follow-the-leader until I had to explain how I felt no restriction to just one gender, then they shut up. They don't really acknowledge it at all and just treat it as a fact of life, as it should be.