Oh I love DnD, Pathfinder, and various other role playing game settings/systems. I am currently running a Pathfinder adventure path, which is basically a whole slew of premade dungeons and encounters designed to take characters from level 1 to 20 all while following a cohesive story, for my friends, two of whom live too far away to physically travel and another one that lives half way across the U.S.. We run it using Skype and a useful little program called Maptools. Maptools lets you essentially have a virtual table where you can put maps and tokens down and everyone just connects to that. Its not that hard to set up and I have managed to get very technologically illiterate people playing on it.
Don't let a lack of players near by stop you from enjoying these wonderful games. With a bit of work you can find groups of people online looking to run or play in games.