Is it a USB or an internal drive? That's an important thing to know. Does it eject when you hit the eject button? Do any lights flash, or does it make any sound during startup as though it were initializing?
First and foremost, check your cables. By whatever means, ensure that there is power to the drive. That is always the first step if it's not showing up in device manager.
If it's an external USB drive, check if the power supply is good, and try multiple USB ports which I'm sure you've already tried.
Try different ports internally, too. I'm going to assume it's a SATA drive if it's internal, since it's 2020, but try swapping the SATA/IDE ports on your mobo with devices that you know are good with things like your HDD/SDD. Your BIOS should still recognize it even without an MBR to look at.
Grab the model number off the drive (should be on a sticker or stamped/engraved somewhere on it), and ensure it's compatible with your release of Windows.
In addition, what release of Windows are you using/specs of your system, because you should be able to just load the drivers on a flash drive and install it that way. It's unusual for a release of W10 to not have some sort of driver to handle your wireless adapter right from the install package.

I haven't had that happen in years.
I'd just use whatever computer you wrote this post with, put the drivers on a flash drive, and install them that way lol.