Is not amused...
Depends on the type of fan, I've noticed this with some people who design their characters to look a bit on the animal side (with digitigrade feet looking more animal) to the nekos.
I have seen both of those. Creeped me out big time..I'd forgotten about this problem until you just brought it back up in my head. I actually did some research on it in a graphic design class. Turns out, some psychologists that think it's a human defense mechanism. Persoannlly, there isn't usually a problem for me becaus the line is pretty thick for me (I notice imperfections in real people that artists rarely add to the faces, making it easy to point out a "fake"). In that sense, I get the creeps from celebrities whose skin looks like rubber after plastic surgery and whatnot. Kind of the opposite of this effect-- because they made themselves look so "human" they became artificial.
But, I did find a rather creepy picture somewhere out of Asia (I assume Japan)
Also, I saw something the BBC did on on "Fake Babies" that was extremely creepy. They actually put in those imperfections, and it was extremely disturbing for some reason.
Turn up the brightness on your screen hurdur.