Hello, I can speak from experience on this subject as well. I've been drawing furry stuff for a few years, trying to improve my drawings, but I always wanted to migrate more towards NSFW things. I did a couple of those here and there in the past years but didn't upload them to my FA page or anywhere else, usually I would only send it to the person and that's that.
Recently though (as in, this past weekend) I finally set in motion a new account to focus on NSFW things. I had been drawing some characters, getting some practice, and coming up with a game plan. I see it more as a new brand so to speak, and I have no connection with my previous account, or myself IRL, but then again, I do this more as a hobby that as a business.
It can be hard to manage two accounts, but it's worth it. Even if you're ok with having your "regular" work associated with NSFW things, I would still advise the creation of a new brand strictly for it, for your sake, and to get a more consistent audience for each of the subjects.
I don't think it makes the art less ... art, but there's no denying even simply watching that sort of thing is looked down on by society. When I created my first account I kept all of it hidden from people I know IRL, but since I became more comfortable with it, I let the name leak out through my online accounts and skype name and what have you, so having them connected in any way is a big no-no. I was already basically living a double life with the last account, so how hard can it be to live a tri-life.
But yes, in an age where employers can easily do a background check on your online presence, I would (and am) completely separate both types of work.